|
| Entrez Id: |
2052 |
| Gene Symbol: |
EPHX1 |
EPHX1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
| Entrez Id: |
64332 |
| Gene Symbol: |
NFKBIZ |
NFKBIZ
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
| Entrez Id: |
6597 |
| Gene Symbol: |
SMARCA4 |
SMARCA4
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
| Entrez Id: |
580 |
| Gene Symbol: |
BARD1 |
BARD1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
| Entrez Id: |
1027 |
| Gene Symbol: |
CDKN1B |
CDKN1B
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
| Entrez Id: |
7518 |
| Gene Symbol: |
XRCC4 |
XRCC4
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
| Entrez Id: |
6224 |
| Gene Symbol: |
RPS20 |
RPS20
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.
|
27713038 |
2017 |
|
| Entrez Id: |
22909 |
| Gene Symbol: |
FAN1 |
FAN1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability.
|
26797144 |
2016 |
|
| Entrez Id: |
1027 |
| Gene Symbol: |
CDKN1B |
CDKN1B
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Tumorigenesis in p27/p53- and p18/p53-double null mice: functional collaboration between the pRb and p53 pathways.
|
15584024 |
2005 |
|
| Entrez Id: |
5795 |
| Gene Symbol: |
PTPRJ |
PTPRJ
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Tumor Suppressor PTPRJ Is a Target of miR-155 in Colorectal Cancer.
|
28316102 |
2017 |
|
| Entrez Id: |
9156 |
| Gene Symbol: |
EXO1 |
EXO1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.310 |
Biomarker |
CLINGEN |
Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies.
|
17452984 |
2007 |
|
| Entrez Id: |
4437 |
| Gene Symbol: |
MSH3 |
MSH3
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Tissue-specific mismatch repair protein expression: MSH3 is higher than MSH6 in multiple mouse tissues.
|
23228367 |
2013 |
|
| Entrez Id: |
1027 |
| Gene Symbol: |
CDKN1B |
CDKN1B
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
The murine gene p27Kip1 is haplo-insufficient for tumour suppression.
|
9823898 |
1998 |
|
| Entrez Id: |
79728 |
| Gene Symbol: |
PALB2 |
PALB2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
The Genotype-Tissue Expression (GTEx) project.
|
23715323 |
2013 |
|
| Entrez Id: |
27030 |
| Gene Symbol: |
MLH3 |
MLH3
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.500 |
Biomarker |
CLINGEN |
The first functional study of MLH3 mutations found in cancer patients.
|
18521850 |
2008 |
|
| Entrez Id: |
4437 |
| Gene Symbol: |
MSH3 |
MSH3
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression.
|
10706084 |
2000 |
|
| Entrez Id: |
472 |
| Gene Symbol: |
ATM |
ATM
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
The depletion of ATM inhibits colon cancer proliferation and migration via B56γ2-mediated Chk1/p53/CD44 cascades.
|
28093285 |
2017 |
|
| Entrez Id: |
5395 |
| Gene Symbol: |
PMS2 |
PMS2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
Biomarker |
CLINGEN |
The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations.
|
18602922 |
2008 |
|
| Entrez Id: |
6597 |
| Gene Symbol: |
SMARCA4 |
SMARCA4
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A.
|
27852072 |
2016 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
The CHEK2 gene I157T mutation and other alterations in its proximity increase the risk of sporadic colorectal cancer in the Czech population.
|
18996005 |
2009 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype.
|
12690581 |
2003 |
|
| Entrez Id: |
4436 |
| Gene Symbol: |
MSH2 |
MSH2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.900 |
Biomarker |
CLINGEN |
Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice.
|
8706033 |
1996 |
|
| Entrez Id: |
5395 |
| Gene Symbol: |
PMS2 |
PMS2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
Biomarker |
CLINGEN |
Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).
|
15872200 |
2005 |
|
| Entrez Id: |
999 |
| Gene Symbol: |
CDH1 |
CDH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Screening E-cadherin in gastric cancer families reveals germline mutations only in hereditary diffuse gastric cancer kindred.
|
11968083 |
2002 |
|
| Entrez Id: |
4436 |
| Gene Symbol: |
MSH2 |
MSH2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.900 |
Biomarker |
CLINGEN |
Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer.
|
27329137 |
2016 |